bBHC is a life sciences company aiming for a youthful 120 years and a healthy 140 years of age.
By considering both humanity and science, as well as humanity and nature, the company conducts comprehensive life science research to contribute to human health and longevity through down aging and treating incurable diseases.
Down Aging using mesenchymal stem cell
bBHC's umbilical cord-derived mesenchymal stem cells produce a variety of substances essential for skin-down aging, demonstrating capabilities significantly superior to other mesenchymal stem cells.
| Effective Factors | Adipose-derived MSC | Umbilical cord-derived MSC |
| bFGF | 1 | 5 |
| VEGF | 1 | 2.12 |
| HGF | 1 | 8.19 |
| KGF | 1 | 2.41 |
| PDGF-AA | 1 | 1.35 |
| TGF-ß1 | 1 | 2.03 |
| Fibronectin | 1 | 2.59 |
| Collagen type 1 | 1 | 6.74 |
bBHC's umbilical cord-derived mesenchymal stem cells enhance the proliferation capacity of keratinocytes, increasing the number of cells that make up the skin. The increase in skin cells leads to collagen accumulation within the skin. As a result, phenotypic changes associated with down aging occur, such as increased skin thickness, improved elasticity, and reduced wrinkles.
