Ability of Differntiation

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Ability of Differntiation
Ability of Differntiation

Differentiation Potential of KHCs
(3 germ layer lineages)

STRI successfully differentiated into endoderm, mesoderm and ectoderm using KHCs.
We differentiated into pancreatic beta cell, hepatocyte, neural cell, hematopoietic stem cell, T-cell, chondrocyte, osteoblast and brown adipocyte.

Pancreatic beta cell (Endoderm) InsulinC-peptideMAFAPDX1

Hematopoietic stem cell (Mesoderm) CD34CD45

Neural cell (Ectoderm) TUJ1GFAP

Ectoderm : Neural cell

Mesoderm : HSC

Mesoderm: T-cell

Mesoderm : Podocyte

Mesoderm: Brown adipocyte

Mesoderm: Chondrocyte

Endoderm : Pancreatic β-cell

Endoderm : Pancreatic β-cell

Endoderm: Hepatocyte